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Precision Biologic Inc normal human reference plasma
Normal Human Reference Plasma, supplied by Precision Biologic Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/reference+normal+human+plasma/pooled+normal+human+plasma/pmc12077799-132-16-20
Average 90 stars, based on 1 article reviews
normal human reference plasma - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Clinical Proteomics:

Article Title: Measuring factor VIII activity in samples from patients treated with N8-GP (Esperoct ® ; turoctocog alfa pegol) during the pathfinder clinical trials programme.
Article Snippet: FVIII activity in samples taken at various time points from 21 patients treated with N8-GP (Esperoct®; turoctocog alfa pegol) during the pathfinder clinical trial programme was assessed and compared using different assay methods.. FVIII activity measurements in samples from patients treated with N8-GP were similar using chromogenic assays, regardless of calibration method or kit/ analyser combination.. FVIII activity measurements using one-stage aPTT-based assays were slightly lower when calibrated using normal human plasma (NHP) compared with a product-specific standard; this difference may be partially attributable to differences in the aPTT reagent/ analyser combinations used to perform the measurements.

Article Title: Aging and ABO blood type influence VWF and FVIII levels through interrelated mechanisms
Article Snippet: .. Normal Human Reference Plasma (NRP) was used as standard (Precision Biologics, Dartmouth, NS, Canada). ..

Article Title: Endogenous fibrinolysis facilitates clot retraction in vivo.
Article Snippet: The fluorogenic substrates used to quantify recombinant human tPA activity after dialysis were tPA SpectroFluor 444FL substrate from American Diagnostica was (ADF Biomedical, France) and Boc-L-(p-F) FPR-ANSN-H-C2H5 from US Biological Life Sciences (MA, USA). .. CRYOcheck Normal Reference Plasma for clot lysis assays and was sourced from Precision BioLogic, Inc. (Canada). .. Inhibitors - Tranexamic acid was from Sigma (Australia).

Article Title: Pediatric Acquired von Willebrand Disease With Berlin Heart Excor Ventricular Assist Device Support.
Article Snippet: Background: The balance of hemostasis and anticoagulation is a concern for patients dependent upon ventricular assist devices (VADs).. Bleeding is a common complication with both shortand long-term use of these devices.. A better understanding of the risk factors and etiologies of bleeding associated with these devices is needed and could improve the overall results.

Article Title: Fragment-based drug discovery for transthyretin kinetic stabilisers using a novel capillary zone electrophoresis method
Article Snippet: .. Briefly, test ligand and 125 I-T 4 (Perkin Elmer Inc., Waltham, MA) were mixed with undiluted normal human reference plasma (Precision Biologic Inc., Nova Scotia, Canada). .. The TTR in plasma was immunoprecipitated by sheep anti-human prealbumin polyclonal antibody (The Binding Site Group Ltd., Birmingham, UK).

Concentration Assay:

Article Title: Measuring factor VIII activity in samples from patients treated with N8-GP (Esperoct ® ; turoctocog alfa pegol) during the pathfinder clinical trials programme.
Article Snippet: FVIII activity in samples taken at various time points from 21 patients treated with N8-GP (Esperoct®; turoctocog alfa pegol) during the pathfinder clinical trial programme was assessed and compared using different assay methods.. FVIII activity measurements in samples from patients treated with N8-GP were similar using chromogenic assays, regardless of calibration method or kit/ analyser combination.. FVIII activity measurements using one-stage aPTT-based assays were slightly lower when calibrated using normal human plasma (NHP) compared with a product-specific standard; this difference may be partially attributable to differences in the aPTT reagent/ analyser combinations used to perform the measurements.

other:

Article Title: Population pharmacokinetics of recombinant factor VIII Fc fusion protein.
Article Snippet: Population pharmacokinetics (PK) of FVIII activity‐time profiles following recombinant factor VIII Fc fusion protein (rFVIIIFc) and recombinant factor VIII (rFVIII) dosing were evaluated in previously treated patients with severe hemophilia A (from two clinical trials).. Potential covariates that may be determinants of variability in FVIII activity were identified.. A 2‐compartment model adequately described the PK of both compounds. vonWillebrand Factor (VWF) concentration was the major covariate for rFVIIIFc clearance, reflecting its protective role in FVIII activity clearance.

Article Title: Factor VIII chimeric and hybrid polypeptides, and methods of use thereof
Article Snippet: FVIII activity was measured by the one-stage clotting (aPTT) assay on a Siemens BCS-XP analyzer using commercial reagents (Dade Actin FSL) with calibration against a normal reference plasma (Precision Biologics CRYOcheckTM) traceable to the World Health Organization (WHO) 5th International Standard (IS) for human plasma.

Article Title: Quantitative and qualitative changes of von Willebrand factor and their impact on mortality in patients with end-stage kidney disease
Article Snippet: von Willebrand factor (vWF) antigen levels are elevated in patients with end-stage kidney disease (ESKD).. We determined the quantitative and qualitative abnormalities of vWF and factors influencing vWF proteolysis in participants with ESKD compared with age-matched controls and determined the association between abnormalities in vWF and mortality over 4 years of follow-up. vWF : Ag and von Willebrand factor propeptide (vWFpp) levels, vWF functional activity (vWF :RCo), vWF multimer profiles, ADAMTS-13, thrombospondin 1 (TSP-1), and interleukin 6 (IL-6) were evaluated before and after a single hemodialysis treatment in 55 individuals with vascular disease and an age-matched group of controls (n U 21). vWF : Ag and vWF activity were significantly higher in the ESKD patients and levels increased further following the dialysis procedure.. The percentage of high molecular weight multimers (%HMWMs) was significantly elevated in the ESKD patients compared with controls.

Lysis:

Article Title: Endogenous fibrinolysis facilitates clot retraction in vivo.
Article Snippet: The fluorogenic substrates used to quantify recombinant human tPA activity after dialysis were tPA SpectroFluor 444FL substrate from American Diagnostica was (ADF Biomedical, France) and Boc-L-(p-F) FPR-ANSN-H-C2H5 from US Biological Life Sciences (MA, USA). .. CRYOcheck Normal Reference Plasma for clot lysis assays and was sourced from Precision BioLogic, Inc. (Canada). .. Inhibitors - Tranexamic acid was from Sigma (Australia).



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